Innovation that protects sperm from stress at collection that could reduce conception

Globally, an estimated 48.5 million couples face infertility challenges. In the U.S. alone, about 6.7 million women (or roughly 11% of the reproductive-age population) have difficulty conceiving.1For every couple undergoing diagnosis or treatment for infertility, the male partner must produce a semen sample.


1Source: The World Health Organization and National Survey of Family Growth, Centers for Disease Control and Prevention [CDC] 2006-2010)

About ProteX

We have revolutionized the male semen collection process by creating a collection container designed to reduce the stress on the sperm during collection and protect it until it is processed for use in treatments. Our goal is to allow the male to produce the best sample possible for an attempted pregnancy.

We started with one simple mission: Develop a cost-effective, alternative collection method that would provide the most favorable environment for semen collection allowing a man to produce the best sample possible, with a goal of increasing pregnancy rates.

Understanding the standard collection process

Regardless of the cause of infertility, there will need to be a viable semen sample to be used during treatment. We want this sample to be best possible and your fertility team will provide you with instructions to help make this possible. This may include instructions on abstinence, lifestyle changes, changes in medication etc., each specific to your individual needs.

When the time comes to collect your sample, you will most likely be asked to collect your semen sample by masturbation. Traditionally this is done into a standard, dry specimen cup. This presents some potential challenges to providing the best sample possible, because changes in the environment, especially temperature, very easily damage sperm. Even if the container has been warmed, by the time the sample is collected, the temperature of the container will be cold enough to damage sperm. In addition, the average human semen sample is only about a teaspoon (about 2ml to 5 ml). When this volume is spread over the bottom of a standard specimen cup, the temperature shifts even more rapidly.

How ProteX can help

ProteX’s patented design provides a protective environment for the semen upon collection. The insulated container, funnels the sample into a small holding well to minimize the surface that is exposed to the environment. These feature help protect the sample from temperature shifts for a much longer time, which reduces the concern about the time required for collection. In fact, it protects it so well, it gives your fertility team the option of allowing you to collect at home, depending on what they determine is most appropriate for your individual care. Most clinics currently do not allow at home collection with traditional specimen cups, is almost impossible to maintain the temperature, getting the sample to the clinic in a timely fashion, usually within an hour, and carries a greater risk of having a compromised sample.

proteX Receptacle

Additional protections

ProteX is designed to allow your fertility team to choose if it is to be used with media of their choice, which can provide additional benefits. By using a small, measured amount of media, additional protections can be provided. These protections can include protection against shifts in pH and allow the sperm to begin adjusting to the life outside the body before being processed in the laboratory.

Reduced stress to sperm and the couple

ProteX provides a more favorable environment for sperm compared to traditional collection methods, resulting in more viable sperm, per sample produced, that can be used for treatment.

The insulating properties protect the sample from temperature shifts for a greater period of time. This gives your fertility team (if deemed appropriate for your individual needs) the option of allowing you to collect at home, which can reduce the stress associated with collecting in a clinical setting.

Developed with the assistance of

Texas Tech University

Texas Tech University

Innovation Hub at Research Park

Talk to your clinic about ProteX today.

Talk to your clinic or physician about the benefits of a more effective male fertility aid.